MDPI signed a multi-year agreement with Proofig AI in September 2025 after a pilot, and began using it first on selected biomedical journals, with plans to extend it to more titles. The editorial team decides whether a manuscript’s image types suit Proofig screening, and the manuscript is uploaded through Proofig’s web interface or an API.
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Proofig AI’s AI-generated image detection finds AI-generated images in scientific manuscripts as part of its image integrity platform, which also checks for duplication and manipulation. The user uploads a PDF or DOCX manuscript, Proofig scans all the images, the user reviews the flagged items with forensic tools such as colour maps, Emboss and histogram equalisation,
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Ethicality is MDPI’s in-house research integrity system, built by its Technology Innovation team with the editorial and research integrity teams. The manuscript is parsed into parts such as title, abstract, authors and body, and several AI tools check those parts for signs of paper mills, AI-generated content, duplicate submissions, citation manipulation and author manipulation, with
